Boost compatible hubs have an enhanced flange distance. This has significant advantages: a flatter spoke angle and improved symmetry allow building a stiffer and stronger wheel, always an advantage, but especially for larger diameter wheels in challenging terrain.
https://www.dtswiss.com/Components/Hubs-MTB/350-boost-FW-en
https://www.dtswiss.com/Components/Hubs-MTB/350-boost-RW-en